Chest pain usually occurs when the lung tumor grows and invades the parietal pleura, the serous membrane that lines the lungs, or the chest wall. It is more common in tumors that affect the periphery of lung tissue.
The chest pain produced by lung cancer is usually sharp and its intensity increases as the tumor grows. The most characteristic is its relationship with respiratory movements: it is aggravated by deep breathing, coughing, and sneezing. It also worsens with the movements of the trunk and is relieved by the immobilization of the affected side, this causes the patient to breathe superficially and to be placed in lateral decubitus to limit the movement of the thorax.