Fever and chills
The susceptibility to infections often leads to an increase in fever and chills. Fever is an inflammatory response, and it is a part of the immune defenses against an invader or detected pathogen. In the study mentioned above, patients with a combination of fever and low granulocyte count had a higher chance of bacteremia.
Thus, as mild as fever may seem, you should pay extra attention to this symptom if you find it along with others on this list. Ask your doctor about your condition and remember there are acute (sudden) and chronic (slowly progressing) presentations of leukemia. Do not be overconfident as this may delay your diagnosis until it is too late.