Blood clotting problems
In some cases, leukemia would result in severe blood clotting problems with uncontrolled bleeding or easy bruising. Patients may have a low platelet count, and since these blood components are responsible for blood clotting, it leads to purple spots all over the skin, easily bleeding gums, nosebleeds, and severe menstrual bleeding in women. This is more common in acute promyelocytic leukemia, a subtype of blood cancer that affects platelets.
In these cases, you should be aware of swelling and changes of color in your legs because there’s a clinical entity called deep vein thrombosis that features a blood clot in your lower extremities obstructing the normal blood flow back to the heart. This blood clot may ultimately migrate to other parts of the body and may cause a stroke or a pulmonary embolism, both life-threatening events that may result from leukemia.