The 10 Most Relevant Signs & Symptoms of Prostate Cancer!

Bone pain

Bone pain
Bone pain

Patients with very severe prostate cancer would also start feeling a dull bone pain as a part of their symptoms. Bone pain associated with prostate cancer arises as a result of a very advanced phase of the disease, when the cancer cells have completely lost their physiological functions, including the structures that bind them to the normal tissue. Thus, they break away from the tumor and start migrating to the blood to be disseminated to the rest of the body in a process called metastasis.

Prostate cancer metastasis usually appears in the bone tissue because they are attracted by some substances secreted by cells in the bone marrow. These cells might stay in the bone tissue for a very long time without giving out any symptom, but when they do, bone pain is one of the first symptoms the patient reports. It is usually worse during the night and improves with movement, which is why it may be confounded with arthritis in some instances. Careful examination, physical exam, and lab tests would allow the doctor to reach a correct diagnosis.

As you can see, some signs and symptoms of prostate cancer are the same experienced by those suffering from an enlarged prostate. Others should be examined carefully, and prostate cancer might not be the first guess. However, having all of the symptoms at once or having a few along with a family history of prostate cancer should warn patients to look for medical attention without delay.

References

Moyer, V. A. (2012). Screening for prostate cancer: US Preventive Services Task Force recommendation statement. Annals of internal medicine, 157(2), 120-134.

Mottet, N., Bellmunt, J., Bolla, M., Briers, E., Cumberbatch, M. G., De Santis, M., … & Lam, T. B. (2017). EAU-ESTRO-SIOG guidelines on prostate cancer. Part 1: screening, diagnosis, and local treatment with curative intent. European urology, 71(4), 618-629.

Albright, F., Stephenson, R. A., Agarwal, N., Teerlink, C. C., Lowrance, W. T., Farnham, J. M., & Albright, L. A. C. (2015). Prostate cancer risk prediction based on complete prostate cancer family history. The Prostate, 75(4), 390-398.