What Causes Liver Failure? | Liver Failure Causes

II. Causes of Chronic Liver Failure

Chronic liver disease develops when the disease progresses gradually over a long time. It leads to liver cirrhosis, in which the new scar tissue replaces the healthy liver tissue. Then, the liver loses its function.

There are a variety of factors that damage the liver and may result in cirrhosis.

Some examples of possible causes include:

  • Too much alcohol intake: It is the most common cause of chronic liver disease in the USA. Alcohol can cause liver swelling, inflammation (alcoholic hepatitis), cirrhosis, and liver cancer. The appearance of symptoms suggests your liver damage despite repair. If you stop drinking alcohol in the fatty liver stage, your liver will reverse its damage.
  • Hepatitis B: liver enlargement occurs, and the liver can’t do its functions as before. You can prevent hepatitis B by vaccination and immunoglobulins.
  • Hepatitis C: spread through the blood. Needles sharing and using dirty syringes for tattoos can spread hepatitis C.
  • Non-alcoholic fatty liver disease occurs as a complication of obesity, diabetes, or high cholesterol level in the blood. It affects heavy drinkers.
  • Hemochromatosis: an inherited condition in which iron deposits in the body over many years.
  • Alpha 1 antitrypsin deficiency: an inherited disease that causes damage to the liver and lung
  • Lysosomal acid lipase deficiency: a genetic condition characterized by the breakdown of fat and cholesterol in your cells.
  • Primary biliary cholangitis: It is a chronic disease that results from the destruction of small bile ducts.
  • Primary sclerosing cholangitis: hardening and scarring of bile ducts
  • Liver adenoma (hepatocellular adenoma): benign tumor of the liver cells. It affects women, especially those taking birth control pills.
  • Liver cancer: It causes permanent damage and liver failure. It also may be linked to obesity and fatty liver disease.

Written by Martin Davis