Crucial Facts About Cholangiocarcinoma (Bile Duct Cancer)

Who is Most Likely to Develop Cholangiocarcinoma?

Who is more likely to develop cholangiocarcinoma?

Cholangiocarcinoma is not the most common type of cancer. It is infrequent compared to others. As hepatocellular cancer gets 15,000 cases every year, cholangiocarcinoma only affects 2500 people in the United States. This would be one case per 100,000 population every year.

The risk factors to develop cholangiocarcinoma include:

  • It is more common in women, especially if they are over 60 years old
  • The incidence is higher in Asian countries (mainly Thailand, China, Japan, and South Korea).
  • Workers who labor at printing companies can be exposed to dichloromethane and other carcinogens that trigger cholangiocarcinoma. Similarly, rubber, wood-finishing, and aircraft workers can be exposed to similar carcinogens.
  • In America, the highest incidence is found in Native Americans.
  • Patients with primary sclerosing cholangitis and chronic inflammation of the bile ducts may have a higher incidence of cholangiocarcinoma.
  • Infections with parasites and bacteria such as Ascaris lumbricoides, Helicobacter pylori, and Clonorchis Sinensis may also increase the risk.
  • There is also a higher risk of cholangiocarcinoma in patients with inflammatory bowel disease.