How is the HPV Virus Transmitted? Human Papillomaviruses Prevention & Treatment

Investigations for Detecting HPV Infection

No specific symptom can track down early infection of HPV infection of the throat. Some harmful or precancerous oropharyngeal HPV infections might be diagnosed during screening or assessment by a dental specialist or medical specialist. Yet, most are diagnosed by screening testing in people who have signs or symptoms of long duration, which do not fit into other common infections.

To investigate a hard-to-see region of the throat, larynx (voice box), and the base of the tongue, specialists, might utilize tiny mirrors. The specialist can use flexible laryngoscopes and pharyngoscopes for specific examination of the throat areas that are not visible easily with mirrors.

The specialist might need to perform a skin biopsy of regions that look doubtful for malignant growths. The cells are then seen to search for disease indications under a magnifying lens. Biopsy tests from skin warts or throat lesions might be tested for the presence of HPV DNA. The presence of HPV DNA flags a malignant growth that is more receptive to treatment than one that is HPV-negative.

References

1. Leslie SW, Sajjad H, Kumar S. Genital Warts. Diagnostics to Pathogenomics of Sexually Transmitted Infections. Published online September 17, 2021:119-133. doi:10.1002/9781119380924
2. STD Facts – Human papillomavirus (HPV). Accessed January 26, 2022. https://www.cdc.gov/std/hpv/stdfact-hpv.htm
3. de Sanjosé S, Brotons M, Pavón MA. The natural history of human papillomavirus infection. Best Practice & Research Clinical Obstetrics & Gynaecology. 2018;47:2-13. doi:10.1016/J.BPOBGYN.2017.08.015
4. Chan CK, Aimagambetova G, Ukybassova T, Kongrtay K, Azizan A. Human Papillomavirus Infection and Cervical Cancer: Epidemiology, Screening, and Vaccination – Review of Current Perspectives. Journal of Oncology. 2019;2019. doi:10.1155/2019/3257939
5. You EL, Henry M, Zeitouni AG. Human Papillomavirus–Associated Oropharyngeal Cancer: Review of Current Evidence and Management. Current Oncology 2019, Vol 26, Pages 119-123. 2019;26(2):119-123. doi:10.3747/CO.26.4819
6. Coudray M, Kiplagat S. Bacterial vaginosis and the risk of human papillomavirus and cervical cancer. American Journal of Obstetrics and Gynecology. 2019;221(2):171-172. doi:10.1016/j.ajog.2019.05.016
7. Yakely AE, Avni-Singer L, Oliveira CR, Niccolai LM. Human Papillomavirus Vaccination and Anogenital Warts: A Systematic Review of Impact and Effectiveness in the United States. Sexually transmitted diseases. 2019;46(4):213. doi:10.1097/OLQ.0000000000000948
8. Petca A, Borislavschi A, Zvanca M, Petca RC, Sandru F, Dumitrascu M. Non-sexual HPV transmission and role of vaccination for a better future (Review). Experimental and therapeutic medicine. 2020;20(6):1-1. doi:10.3892/ETM.2020.9316
9. Roden RBS, Stern PL. Opportunities and challenges for human papillomavirus vaccination in cancer. Nature Reviews Cancer 2018 18:4. 2018;18(4):240-254. doi:10.1038/nrc.2018.13