Intrahepatic causes
- Viral hepatitis: Viral hepatic diseases cause inflammation and swelling in the organ. The metabolic function may stay normal, but there’s an increase of direct bilirubin.
- Cirrhosis and alcoholic hepatitis: Alcohol and fatty liver disease cause inflammation in the liver, with a similar increase of bilirubin as noted in viral hepatitis. When this problem continues for a long time, the patient develops cirrhosis, and there’s a deformation of the liver structure with significant problems transporting bile.




