Progressive Familial Intrahepatic Cholestasis (PFIC) | PFIC Liver

Symptoms of PIFC

PIFC symptoms are mainly due to liver affections, as follows:

• Fatigue
• Itching due to the deposition of bile salts in our body
• Enlarged liver and spleen (Hepatosplenomegaly)
• Jaundice: Yellowish discoloration of skin and eye
• Gall bladder stone
• Weight loss due to impaired absorption of fats
• Impaired absorption of fat-soluble vitamins (A, D, E, K), which leads to their deficiency
• Liver cell failure and cirrhosis (scarring)
• Liver cancer