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Obesity
Skin tag growth might be affected by your weight. It could be due to increased friction in the areas where your skin rubs together. Being overweight or obese can lead to metabolic abnormalities in the body, which results in extra skin cells development. Obesity causes hyperleptemia because leptin is present in free form in obese people, whereas leptin is present in bound form in lean people. It suggests that in most obese people, obesity is a leptin-resistant state rather than a disorder caused by a faulty ob gene. Leptin stimulates the growth and proliferation of epidermal and dermal cells via binding to leptin receptors in the skin.
